Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994204 | 0.92 | TSHR (0.53) | TSHRNPC1RAB9ABACE1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27533472 | 0.91 | TSHR (0.55) | TSHRNPC1RAB9ABACE1ALDH1A1 | |
| SCHEMBL16555730 | 0.82 | TSHR (0.54) | NAAAEPHX1TSHRCTSCNPC1 | |
| SCHEMBL993722 | 0.80 | TDP1 (0.45) | RAB9ACYP3A4KDM4EALDH1A1KMT2A | |
| SCHEMBL993720 | 0.80 | TDP1 (0.45) | RAB9ACYP3A4KDM4EALDH1A1KMT2A | |
| SCHEMBL993723 | 0.80 | TDP1 (0.45) | RAB9ACYP3A4KDM4EALDH1A1KMT2A | |
| SCHEMBL2513942 | 0.80 | TDP1 (0.45) | RAB9ACYP3A4KDM4EALDH1A1KMT2A | |
| SCHEMBL23485377 | 0.80 | TSHR (0.51) | TSHRCTSCNPC1RAB9ABACE1 | |
| SCHEMBL10137745 | 0.80 | TSHR (0.51) | TSHRCTSCNPC1RAB9ABACE1 | |
| SCHEMBL9636938 | 0.80 | TSHR (0.51) | TSHRCTSCNPC1RAB9ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |