Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 19/20 | 0.76 |
| ▸ | ELOC | Q15369 | 5/20 | 0.76 |
| ▸ | ELOB | Q15370 | 5/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15111704 | 1.00 | VHL (0.76) | VHLELOCELOB | |
| SCHEMBL15126142 | 0.94 | VHL (0.82) | VHLELOCELOB | |
| SCHEMBL16266986 | 0.94 | VHL (0.82) | VHLELOCELOB | |
| SCHEMBL15125957 | 0.93 | VHL (0.80) | VHLELOCELOB | |
| SCHEMBL21696924 | 0.93 | VHL (0.80) | VHLELOCELOB | |
| SCHEMBL15125925 | 0.92 | VHL (0.78) | VHLELOCELOB | |
| SCHEMBL15125956 | 0.92 | VHL (0.75) | VHLELOCELOB | |
| SCHEMBL15125932 | 0.91 | VHL (0.77) | VHLELOCELOB | |
| SCHEMBL15126365 | 0.91 | VHL (0.76) | VHLELOCELOB | |
| SCHEMBL15126073 | 0.90 | VHL (0.72) | VHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |