Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 16/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 8/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16160691 | 1.00 | SLC5A2 (0.44) | SLC5A2SLC5A1CHRM1ADRA1ASLC6A3 | |
| SCHEMBL13271737 | 0.87 | SLC5A2 (0.47) | SLC5A2SLC5A1CHRM1ADRA1ASLC6A3 | |
| SCHEMBL21697555 | 0.87 | SLC5A2 (0.47) | SLC5A2SLC5A1CHRM1ADRA1ASLC6A3 | |
| SCHEMBL21697626 | 0.87 | SLC5A2 (0.47) | SLC5A2SLC5A1CHRM1ADRA1ASLC6A3 | |
| SCHEMBL16160680 | 0.86 | SLC5A2 (0.59) | SLC5A2SLC5A1CHRM1ADRA1ASLC6A3 | |
| SCHEMBL16160662 | 0.86 | SLC5A2 (0.48) | SLC5A2SLC5A1CHRM1ADRA1ASLC6A3 | |
| SCHEMBL12662862 | 0.86 | SLC5A2 (0.48) | SLC5A2SLC5A1CHRM1ADRA1ASLC6A3 | |
| SCHEMBL21697550 | 0.86 | SLC5A2 (0.59) | SLC5A2SLC5A1CHRM1ADRA1ASLC6A3 | |
| SCHEMBL16009613 | 0.85 | SLC5A2 (0.50) | SLC5A2SLC5A1CHRM1ADRA1ASLC6A3 | |
| SCHEMBL16009616 | 0.85 | SLC5A2 (0.50) | SLC5A2SLC5A1CHRM1ADRA1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968258-B1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-12 | — | — | EP | disclosed |