SCHEMBL21697865

SCHEMBL21697865

O=NC(=O)CN(CC(=O)O)c1ccccc1OCCOc1ccccc1N(CC(=O)O)CC(=O)O

nearest known ligand 0.80

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.80
ALDH1A1 P00352 5/20 0.39
KMT2A Q03164 2/20 0.39
PTK2B Q14289 1/20 0.39
LMNA P02545 4/20 0.38
SLC6A9 P48067 7/20 0.38
SMN1; SMN2 Q16637 4/20 0.35
KDM4E B2RXH2 2/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 2/20 0.34
JAK2 O60674 1/20 0.34
GAA P10253 1/20 0.34
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31185081 0.89 TDP1 (1.00) TDP1ALDH1A1KMT2APTK2BLMNA
SCHEMBL232103 0.89 TDP1 (1.00) TDP1ALDH1A1KMT2APTK2BLMNA
Ethane SCHEMBL28264318 0.86 TDP1 (0.93) TDP1ALDH1A1KMT2APTK2BLMNA
SCHEMBL17640377 0.82 TDP1 (0.85) TDP1ALDH1A1KMT2APTK2BLMNA
SCHEMBL13235779 0.81 TDP1 (0.82) TDP1ALDH1A1KMT2APTK2BLMNA
SCHEMBL13560703 0.81 TDP1 (0.82) TDP1ALDH1A1KMT2APTK2BLMNA
SCHEMBL24026056 0.80 TDP1 (0.80) TDP1ALDH1A1KMT2APTK2BLMNA
SCHEMBL14654335 0.80 TDP1 (0.80) TDP1ALDH1A1KMT2APTK2BLMNA
SCHEMBL17707465 0.79 TDP1 (0.78) TDP1ALDH1A1KMT2APTK2BLMNA
SCHEMBL31344167 0.79 TDP1 (0.78) TDP1ALDH1A1KMT2APTK2BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3291361-B1 ELECTROLYTE ADDITIVES FOR MAGNESIUM AIR BATTERIES HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2020-02-12 EP disclosed