Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21698420 | 0.87 | CNR2 (0.42) | S1PR1ACACBCNR2CYP2C19CNR1 | |
| SCHEMBL10251494 | 0.85 | MEN1 (0.43) | S1PR1ACACBCNR2CYP2C19CNR1 | |
| SCHEMBL21698390 | 0.77 | S1PR1 (0.40) | S1PR1CYP2C19MLYCDCYP3A4 | |
| SCHEMBL21698427 | 0.77 | S1PR1 (0.40) | S1PR1CYP2C19MLYCDCYP3A4 | |
| SCHEMBL16256875 | 0.77 | GRM2 (0.51) | CNR2CYP2C19CNR1GRM2MEN1 | |
| SCHEMBL18090934 | 0.76 | GRM2 (0.48) | ACACBCNR2CYP2C19CNR1GRM2 | |
| SCHEMBL20001367 | 0.74 | CNR2 (0.50) | CNR2CYP2C19CNR1GRM2MEN1 | |
| SCHEMBL12545817 | 0.74 | CYP2D6 (0.55) | MEN1KMT2AKDM4ETP53CYP2D6 | |
| SCHEMBL10238327 | 0.74 | MEN1 (0.47) | ACACBCNR2CYP2C19CNR1GRM2 | |
| SCHEMBL8058929 | 0.74 | KDM4E (0.50) | CYP2C19GRM2MEN1KMT2AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280716-B1 | IMIDAZO[1,2-A]PYRIDIN-2-YL DERIVATIVES AS PESTICIDES AND INTERMEDIATES THEREOF | BAYER CROPSCIENCE AG (DE) | 2020-02-12 | — | — | EP | disclosed |