Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709881 | 0.91 | PTGDR2 (0.58) | PTGDR2USP2 | |
| SCHEMBL709895 | 0.90 | PTGDR2 (0.58) | PTGDR2MEN1KMT2A | |
| SCHEMBL708235 | 0.89 | PTGDR2 (0.56) | PTGDR2MEN1KMT2AUSP2 | |
| SCHEMBL711593 | 0.89 | PTGDR2 (0.56) | PTGDR2 | |
| SCHEMBL710467 | 0.89 | PTGDR2 (0.56) | PTGDR2 | |
| SCHEMBL716116 | 0.88 | PTGDR2 (0.52) | PTGDR2USP2 | |
| SCHEMBL709999 | 0.86 | PTGDR2 (0.56) | PTGDR2 | |
| SCHEMBL27823476 | 0.84 | PTGDR2 (0.49) | PTGDR2 | |
| SCHEMBL710348 | 0.82 | USP2 (0.55) | PTGDR2MEN1KMT2AUSP2 | |
| SCHEMBL709910 | 0.81 | PTGDR2 (0.54) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346807-A1 | NAPHTHYLACETIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2011-07-27 | — | — | EP | claimed |
| WO-2010055005-A1 | NAPHTHYLACETIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-05-20 | — | — | WO | claimed |
| EP-2346807-A1 | NAPHTHYLACETIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010055005-A1 | NAPHTHYLACETIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-05-20 | — | — | WO | disclosed |