Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24759092 | 1.00 | KLKB1 (0.83) | KLKB1KLK1 | |
| SCHEMBL17268102 | 0.95 | KLKB1 (0.91) | KLKB1KLK1 | |
| SCHEMBL21699873 | 0.95 | KLKB1 (0.91) | KLKB1KLK1 | |
| SCHEMBL23517198 | 0.95 | KLKB1 (0.91) | KLKB1KLK1 | |
| SCHEMBL14555079 | 0.95 | KLKB1 (0.91) | KLKB1KLK1 | |
| Hydrochloric Acid SCHEMBL14485639 | 0.94 | KLKB1 (0.89) | KLKB1KLK1 | |
| Hydrochloric Acid SCHEMBL20136153 | 0.94 | KLKB1 (0.89) | KLKB1KLK1 | |
| SCHEMBL15901297 | 0.91 | KLKB1 (0.83) | KLKB1KLK1 | |
| SCHEMBL14488775 | 0.91 | KLKB1 (0.83) | KLKB1KLK1 | |
| SCHEMBL21669910 | 0.90 | KLKB1 (0.88) | KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729443-B3 | BENZYLAMINE DERIVATIVES AS INHIBITORS OF PLASMA KALLIKREIN | KALVISTA PHARMACEUTICALS LTD (GB) | 2020-02-12 | — | — | EP | disclosed |