Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361355 | 0.93 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL1049510 | 0.93 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1NPC1RAB9AHSD17B10 | |
| Iodomethane SCHEMBL28083731 | 0.89 | SMN1; SMN2 (0.57) | SMN1; SMN2NPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL92781 | 0.89 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1NPC1RAB9AHSD17B10 | |
| Propane SCHEMBL28083723 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2NPSR1NPC1RAB9AHSD17B10 | |
| Bromide SCHEMBL10996884 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL2186277 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2NPSR1NPC1RAB9AHSD17B10 | |
| Propane SCHEMBL28083730 | 0.84 | HSD17B10 (0.59) | SMN1; SMN2NPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL2171446 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1NPC1RAB9AHSD17B10 | |
| SCHEMBL17865395 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1NPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346956-A1 | ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES | Loctite (R & D) Limited (IE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010046412-A1 | ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES | LOCTITE (R & D) LIMITED (IE) | 2010-04-29 | — | — | WO | disclosed |