⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596769 | 0.78 | — | — | |
| SCHEMBL16961405 | 0.77 | NPC1 (0.32) | — | |
| SCHEMBL160296 | 0.76 | — | — | |
| SCHEMBL4587807 | 0.73 | HRH3 (0.42) | — | |
| SCHEMBL61322 | 0.71 | — | — | |
| SCHEMBL3924093 | 0.67 | TAAR1 (0.41) | — | |
| SCHEMBL3518 | 0.66 | — | — | |
| SCHEMBL2073678 | 0.65 | — | — | |
| SCHEMBL15063991 | 0.63 | NPC1 (0.41) | — | |
| SCHEMBL7498491 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102827056-A | N-aryl-substituted pyrrolidone derivative and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2012-12-19 | — | — | CN | claimed |
| CN-102741256-A | Bicyclic heteroaryl derivatives having inhibitory activity for protein kinase | HANMI PHARM IND CO LTD | 2012-10-17 | — | — | CN | claimed |
| JP-4716984-B2 | — | — | 2011-07-06 | — | — | JP | claimed |
| CN-102083794-A | Urea compounds as gamma secretase modulators | AMGEN INC | 2011-06-01 | — | — | CN | claimed |
| CN-102036990-A | Novel tyrosine kinase inhibitors | CHEMBRIDGE CORP | 2011-04-27 | — | — | CN | claimed |
| CN-101151249-B | Cyclopentapyridine and tetrahydroquinoline derivatives | PFIZER PRODUCTS INC. (US) | 2011-04-06 | — | — | CN | claimed |
| CN-101801962-A | Trisubstituted pyrimidine derivatives for the treatment of proliferative diseases | ASTRAZENECA AB | 2010-08-11 | — | — | CN | claimed |
| CN-101506194-A | Novel pyridine analogs | ASTRAZENECA AB (SE) | 2009-08-12 | — | — | CN | claimed |
| CN-101365445-A | Treatment of Length-Dependent Neuropathy | ARCION THERAPEUTICS INC (US) | 2009-02-11 | — | — | CN | claimed |
| EP-1809600-A4 | CYCLIC B-AMINO ACID DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-01-14 | — | — | EP | claimed |
| CN-1547584-A | Substituted 1-oxa-2,8-diaza-spiro[4,5]dec-2-ene derivatives and related treatment methods | — | 2004-11-17 | — | — | CN | claimed |
| US-20040214808-A1 | Linear chain substituted monocyclic and bicyclic derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-10-28 | — | — | US | claimed |
| US-20040209863-A1 | Sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-10-21 | — | — | US | claimed |
| US-20040204454-A1 | Lactam-containing cyclic diamines and derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-10-14 | — | — | US | claimed |
| WO-2004083177-A2 | LINEAR CHAIN SUBSTITUTED MONOCYCLIC AND BICYCLIC DERIVATIVES AS FACTOR XA INHIBITORS | BRYSTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | claimed |
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | claimed |
| WO-2004083174-A2 | SULFONYL-AMIDINO CONTAINING AND TETRAHYDROPYRIMIDINO CONTAINING COMPOUNDS AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | claimed |
| WO-2003099276-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | claimed |
| CN-1247537-A | Sulfonamide compounds having 5-HT receptor activity | KNOLL AG (DE) | 2000-03-15 | — | — | CN | claimed |
| CN-1096293-A | Replacement pipecolinic acid derivative as the hiv protease inhibitor | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1994-12-14 | — | — | CN | claimed |