Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 4/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.33 |
| ▸ | KDM4A | O75164 | 3/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.33 |
| ▸ | KDM3B | Q7LBC6 | 3/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005845 | 0.82 | HCAR2 (0.39) | HCAR3MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28015073 | 0.74 | TDP1 (0.36) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL29715766 | 0.73 | TDP1 (0.35) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL27958473 | 0.72 | MEN1 (0.35) | MEN1KMT2AALDH1A1TSHRGABRP | |
| SCHEMBL19250963 | 0.72 | CYP3A4 (0.33) | — | |
| SCHEMBL24345960 | 0.71 | TSHR (0.31) | TSHR | |
| SCHEMBL14822490 | 0.71 | HCAR2 (0.43) | MEN1KMT2AALDH1A1TSHRKDM6B | |
| SCHEMBL7248717 | 0.69 | TDP1 (0.33) | TSHRTDP1 | |
| SCHEMBL2089714 | 0.68 | TDP1 (0.32) | TSHRTDP1 | |
| SCHEMBL272809 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200046699-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | INHIBIKASE THERAPEUTICS, INC. | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200046699-A1 | COMPOSITIONS AND METHODS FOR INHIBITING KINASES | ABL1, FYN, PTK2 | HCAR3 3858/4885MEN1 4399/4885KMT2A 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.