Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28657596 | 1.00 | HDAC1 (0.44) | HDAC1HDAC8HDAC6FKBP1AELANE | |
| SCHEMBL18740361 | 1.00 | HDAC1 (0.44) | HDAC1HDAC8HDAC6FKBP1AELANE | |
| SCHEMBL6157119 | 0.90 | F10 (0.46) | FKBP1AKMT2ARECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL31110438 | 0.88 | KCNH2 (0.48) | — | |
| SCHEMBL16874697 | 0.88 | MAPT (0.42) | — | |
| SCHEMBL18768514 | 0.88 | MAPT (0.42) | — | |
| SCHEMBL16874603 | 0.88 | KCNH2 (0.48) | — | |
| SCHEMBL16874601 | 0.88 | KCNH2 (0.48) | — | |
| SCHEMBL16874694 | 0.88 | MAPT (0.42) | — | |
| SCHEMBL18740387 | 0.86 | KCNH2 (0.47) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033707-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |