⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054697 | 0.79 | — | — | |
| SCHEMBL24148942 | 0.73 | — | — | |
| SCHEMBL20419522 | 0.73 | — | — | |
| SCHEMBL20432787 | 0.73 | — | — | |
| SCHEMBL18550516 | 0.73 | — | — | |
| SCHEMBL18699655 | 0.73 | — | — | |
| SCHEMBL18509764 | 0.71 | — | — | |
| SCHEMBL469714 | 0.71 | — | — | |
| SCHEMBL20991933 | 0.69 | — | — | |
| SCHEMBL20119979 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033707-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |