Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21701274 | 1.00 | BTK (0.61) | BTKJAK3 | |
| SCHEMBL21701262 | 0.91 | BTK (0.68) | BTKJAK3 | |
| SCHEMBL21705070 | 0.91 | BTK (0.68) | BTKJAK3 | |
| SCHEMBL21704903 | 0.90 | BTK (0.67) | BTKJAK3 | |
| SCHEMBL21701264 | 0.90 | BTK (0.67) | BTKJAK3 | |
| SCHEMBL21701305 | 0.88 | JAK3 (0.57) | BTKJAK3 | |
| SCHEMBL21678574 | 0.88 | JAK3 (0.57) | BTKJAK3 | |
| SCHEMBL21678398 | 0.85 | JAK3 (0.72) | BTKJAK3 | |
| SCHEMBL21678489 | 0.85 | JAK3 (0.72) | BTKJAK3 | |
| SCHEMBL21678713 | 0.85 | JAK3 (0.72) | BTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033955-A1 | PYRROLOPYRIMIDINE ITK INHIBITORS | ACLARIS THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |