Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29379388 | 1.00 | HDAC8 (0.35) | HDAC8KCNK3KCNK9DHODHGPBAR1 | |
| SCHEMBL21707903 | 0.92 | HDAC8 (0.39) | HDAC8KCNK3KCNK9GPBAR1HDAC1 | |
| SCHEMBL23264273 | 0.92 | KCNK3 (0.37) | HDAC8KCNK3KCNK9DHODHGPBAR1 | |
| SCHEMBL21707892 | 0.91 | HDAC8 (0.33) | HDAC8RXFP1 | |
| SCHEMBL29738321 | 0.91 | HDAC8 (0.33) | HDAC8RXFP1 | |
| SCHEMBL23264279 | 0.91 | PDE4B (0.34) | HDAC8DHODHGPBAR1HDAC1HDAC6 | |
| SCHEMBL29431906 | 0.91 | PDE4B (0.34) | HDAC8DHODHGPBAR1HDAC1HDAC6 | |
| SCHEMBL21707901 | 0.89 | HDAC8 (0.39) | HDAC8KCNK3KCNK9DHODHGPBAR1 | |
| SCHEMBL21693652 | 0.88 | HDAC8 (0.36) | HDAC8KCNK3KCNK9GPBAR1HDAC1 | |
| SCHEMBL21707905 | 0.88 | HDAC8 (0.38) | HDAC8KCNK3KCNK9GPBAR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767907-B | Pharmaceutical composition containing m-diamide compounds and application thereof | 南通泰禾化工股份有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-113767908-B | Pharmaceutical composition containing m-diamide compound and application thereof | 南通泰禾化工股份有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-110028423-B | Meta-diamide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110810410-B | Pharmaceutical composition containing m-diamide compound and application thereof | 南通泰禾化工股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-113767908-A | Pharmaceutical composition containing m-diamide compound and application thereof | 南通泰禾化工股份有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-113767907-A | Pharmaceutical composition containing m-diamide compound and application thereof | 南通泰禾化工股份有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-113729015-A | Pharmaceutical composition containing m-diamide compound and application thereof | 南通泰禾化工股份有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-110810413-B | Pharmaceutical composition containing m-diamide compound and application thereof | 南通泰禾化工股份有限公司 | 2021-11-23 | — | — | CN | disclosed |
| CN-110810409-B | Pharmaceutical composition containing m-diamide compound and application thereof | 南通泰禾化工股份有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-110810412-B | Pharmaceutical composition containing m-diamide compound and application thereof | 苏州佳辉化工有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-110810414-B | Pharmaceutical composition containing m-diamide compound and application thereof | 苏州佳辉化工有限公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-110810414-A | Pharmaceutical composition containing m-diamide compound and application thereof | 苏州佳辉化工有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110810413-A | Pharmaceutical composition containing m-diamide compound and application thereof | 上海泰禾国际贸易有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110810409-A | Pharmaceutical composition containing m-diamide compound and application thereof | 上海泰禾国际贸易有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110810410-A | Pharmaceutical composition containing m-diamide compound and application thereof | 上海泰禾国际贸易有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-110810412-A | Pharmaceutical composition containing m-diamide compound and application thereof | 苏州佳辉化工有限公司 | 2020-02-21 | — | — | CN | disclosed |
| WO-2020030092-A1 | PHARMACEUTICAL COMPOSITION CONTAINING M-DIAMIDE COMPOUND AND APPLICATION THEREOF | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |
| WO-2020030095-A1 | PHARMACEUTICAL COMPOSITION CONTAINING META-DIAMIDE COMPOUND AND USE THEREOF | 上海泰禾国际贸易有限公司 | 2020-02-13 | — | — | WO | disclosed |