Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 9/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21705139 | 0.93 | PDE5A (0.61) | PDE5A | |
| SCHEMBL23937276 | 0.90 | PDE5A (0.57) | PDE5A | |
| SCHEMBL21705354 | 0.86 | PDE5A (0.68) | PDE5A | |
| SCHEMBL23937265 | 0.86 | PDE5A (0.68) | PDE5A | |
| SCHEMBL21705359 | 0.84 | PDE5A (0.57) | PDE5A | |
| SCHEMBL26047969 | 0.84 | PDE5A (0.57) | PDE5A | |
| SCHEMBL8487807 | 0.83 | PDE5A (0.78) | PDE5A | |
| SCHEMBL21705353 | 0.83 | PDE5A (0.78) | PDE5A | |
| SCHEMBL24402685 | 0.83 | PDE5A (0.65) | PDE5A | |
| SCHEMBL21705137 | 0.80 | PDE5A (0.56) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030489-A1 | NITRIC OXIDE RELEASING PHOSPHODIESTERASE TYPE 5 INHIBITOR | NICOX S.A. (FR) | 2020-02-13 | — | — | WO | disclosed |