Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 13/20 | 0.51 |
| ▸ | RPS6KA2 | Q15349 | 5/20 | 0.51 |
| ▸ | PRKD2 | Q9BZL6 | 5/20 | 0.51 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.47 |
| ▸ | LCP2 | Q13094 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21693807 | 1.00 | MAP4K1 (0.51) | MAP4K1RPS6KA2PRKD2MAP3K5LCP2 | |
| SCHEMBL28405805 | 0.87 | MAP4K1 (0.50) | MAP4K1RPS6KA2PRKD2MAP3K5LCP2 | |
| SCHEMBL21693749 | 0.87 | MAP4K1 (0.50) | MAP4K1RPS6KA2PRKD2MAP3K5LCP2 | |
| SCHEMBL30227850 | 0.85 | MAP4K1 (0.48) | MAP4K1RPS6KA2PRKD2MAP3K5LCP2 | |
| SCHEMBL25735201 | 0.85 | MAP4K1 (0.48) | MAP4K1RPS6KA2PRKD2MAP3K5LCP2 | |
| SCHEMBL21722363 | 0.83 | MAP3K5 (0.58) | MAP4K1RPS6KA2PRKD2MAP3K5LCP2 | |
| SCHEMBL22466066 | 0.83 | MAP3K5 (0.58) | MAP4K1RPS6KA2PRKD2MAP3K5LCP2 | |
| SCHEMBL21693760 | 0.83 | MAP3K5 (0.58) | MAP4K1RPS6KA2PRKD2MAP3K5LCP2 | |
| SCHEMBL28890696 | 0.80 | MAP3K5 (0.47) | MAP4K1RPS6KA2PRKD2MAP3K5LCP2 | |
| SCHEMBL21693769 | 0.80 | MAP3K5 (0.47) | MAP4K1RPS6KA2PRKD2MAP3K5LCP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132984-A | Salts of apoptosis signal-regulating kinase 1 inhibitors and crystalline forms thereof | 江苏豪森药业集团有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-111107848-A | Pharmaceutical composition containing amide derivatives, and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2020-05-05 | — | — | CN | disclosed |
| WO-2020030107-A1 | PHARMACEUTICAL COMPOSITION CONTAINING AMIDE DERIVATIVES, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 江苏豪森药业集团有限公司 | 2020-02-13 | — | — | WO | disclosed |