Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21707446 | 0.95 | LPAR3 (0.59) | LPAR3LPAR1TLR2GRIA1NOD1 | |
| SCHEMBL21724488 | 0.90 | LPAR3 (0.54) | LPAR3LPAR1TLR2NOD1EPHX2 | |
| SCHEMBL27104455 | 0.90 | LPAR3 (0.54) | LPAR3LPAR1TLR2NOD1EPHX2 | |
| SCHEMBL21724702 | 0.90 | LPAR3 (0.54) | LPAR3LPAR1TLR2NOD1EPHX2 | |
| SCHEMBL21724489 | 0.90 | LPAR3 (0.54) | LPAR3LPAR1TLR2NOD1EPHX2 | |
| SCHEMBL24612765 | 0.90 | GRIA1 (0.58) | LPAR3LPAR1TLR2GRIA1SIRT6 | |
| SCHEMBL21724700 | 0.90 | LPAR3 (0.54) | LPAR3LPAR1TLR2NOD1EPHX2 | |
| SCHEMBL24612764 | 0.88 | LPAR3 (0.53) | LPAR3LPAR1TLR2GRIA1NOD1 | |
| SCHEMBL21724669 | 0.88 | TLR2 (0.53) | LPAR3LPAR1TLR2GRIA1NOD1 | |
| SCHEMBL21724668 | 0.88 | TLR2 (0.53) | LPAR3LPAR1TLR2GRIA1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200048187-A1 | LIPOPEPTIDE COMPOUNDS FOR THE TREATMENT OF PAIN DISORDERS | UNIVERSITE DE MONTPELLIER (FR) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048187-A1 | LIPOPEPTIDE COMPOUNDS FOR THE TREATMENT OF PAIN DISORDERS | VIP, FABP2, TRPV1 | LPAR3 132/4885LPAR1 104/4885TLR2 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.