Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15371491 | 0.88 | NR1H2 (0.67) | NR1H2DDR1ALDH1A1KDM4EATM | |
| SCHEMBL19918059 | 0.88 | NR1H2 (0.52) | NR1H2DDR1ALDH1A1KDM4EATM | |
| SCHEMBL21480393 | 0.86 | NR1H2 (0.51) | NR1H2DDR1ALDH1A1KDM4EATM | |
| SCHEMBL12426559 | 0.85 | NR1H2 (0.52) | NR1H2DDR1ALDH1A1KDM4EATM | |
| SCHEMBL19917862 | 0.84 | NR1H2 (0.48) | NR1H2DDR1ALDH1A1KDM4EATM | |
| SCHEMBL29958917 | 0.84 | NR1H2 (0.73) | NR1H2DDR1ALDH1A1KDM4EATM | |
| SCHEMBL1408506 | 0.84 | NR1H2 (0.73) | NR1H2DDR1ALDH1A1KDM4EATM | |
| SCHEMBL20075993 | 0.83 | POLB (0.64) | NR1H2ALDH1A1KDM4EATMPOLB | |
| SCHEMBL9609590 | 0.83 | NR1H2 (0.50) | NR1H2DDR1ALDH1A1KDM4EATM | |
| SCHEMBL10268732 | 0.83 | NR1H2 (0.50) | NR1H2DDR1ALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200048288-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048288-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | MAP3K6, PIK3CA, MAP3K20 | NR1H2 3928/4885DDR1 715/4885ALDH1A1 4677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.