Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.54 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171023 | 1.00 | CHRNB4 (0.54) | CHRNB4CHRNA3IRAK4CNR2MAP2K1 | |
| SCHEMBL1974225 | 0.81 | CNR2 (0.59) | CHRNB4CHRNA3IRAK4CNR2MAP2K1 | |
| SCHEMBL3627815 | 0.81 | CNR2 (0.59) | CHRNB4CHRNA3IRAK4CNR2MAP2K1 | |
| SCHEMBL1974220 | 0.81 | CNR2 (0.59) | CHRNB4CHRNA3IRAK4CNR2MAP2K1 | |
| SCHEMBL32691652 | 0.81 | CHRNB4 (0.67) | CHRNB4CHRNA3IRAK4CHRNB2CHRNA4 | |
| SCHEMBL524008 | 0.80 | CHRNB4 (0.66) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL2170919 | 0.78 | CNR2 (0.56) | CHRNB4CHRNA3IRAK4CNR2CHRNB2 | |
| SCHEMBL2170926 | 0.78 | CNR2 (0.56) | CHRNB4CHRNA3IRAK4CNR2CHRNB2 | |
| SCHEMBL7036348 | 0.76 | CHRNB4 (0.70) | CHRNB4CHRNA3MAP2K1CHRNB2CHRNA4 | |
| SCHEMBL3614551 | 0.73 | CHRNB4 (0.69) | CHRNB4CHRNA3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346843-A2 | SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2011-07-27 | — | — | EP | claimed |
| WO-2010028338-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-11 | — | — | WO | claimed |