Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21710140 | 0.92 | S1PR1 (0.62) | S1PR1S1PR5S1PR3 | |
| SCHEMBL21710142 | 0.92 | S1PR1 (0.62) | S1PR1S1PR5S1PR3 | |
| SCHEMBL21710074 | 0.92 | S1PR1 (0.62) | S1PR1S1PR5S1PR3 | |
| SCHEMBL21710045 | 0.88 | S1PR1 (0.58) | S1PR1S1PR5S1PR2S1PR3 | |
| SCHEMBL21710046 | 0.88 | S1PR1 (0.58) | S1PR1S1PR5S1PR2S1PR3 | |
| SCHEMBL21710103 | 0.88 | S1PR1 (0.58) | S1PR1S1PR5S1PR2S1PR3 | |
| SCHEMBL21710095 | 0.87 | S1PR1 (0.56) | S1PR1S1PR5S1PR2S1PR3 | |
| SCHEMBL21710138 | 0.87 | S1PR1 (0.56) | S1PR1S1PR5S1PR2S1PR3 | |
| SCHEMBL21710081 | 0.87 | S1PR1 (0.56) | S1PR1S1PR5S1PR2S1PR3 | |
| SCHEMBL21710156 | 0.86 | S1PR1 (0.63) | S1PR1S1PR5S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590929-B1 | SPIRO COMPOUND AND USE THEREOF | MEDSHINE DISCOVERY INC (CN) | 2021-09-15 | — | — | EP | disclosed |
| US-10981900-B2 | Spiro compound and use thereof | MEDSHINE DISCOVERY INC. (CN) | 2021-04-20 | — | — | US | disclosed |
| US-20200048235-A1 | SPIRO COMPOUND AND USE THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048235-A1 | SPIRO COMPOUND AND USE THEREOF | S1PR1, S1PR2, S1PR3 | S1PR1 1/4885S1PR5 5/4885S1PR2 2/4885 |
| US-10981900-B2 | Spiro compound and use thereof | S1PR1, S1PR2, S1PR3 | S1PR1 1/4885S1PR5 5/4885S1PR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.