Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14573207 | 0.85 | MAPT (0.54) | MAPTALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL15569388 | 0.82 | MAPT (0.62) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6990807 | 0.82 | MAPT (0.62) | MAPTALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL30414662 | 0.80 | MAPT (0.55) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL25697926 | 0.79 | MAPT (0.58) | MAPTALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL4172495 | 0.79 | MAPT (0.58) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1712956 | 0.79 | MAPT (0.58) | MAPTALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL7570551 | 0.79 | HRH3 (0.48) | MAPTALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL18172778 | 0.78 | MEN1 (0.51) | MAPTALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL378609 | 0.78 | MAPT (0.57) | MAPTALDH1A1KDM4EKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033669-A1 | ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF | FIRMENICH INCORPORATED (US) | 2020-02-13 | — | — | WO | disclosed |