Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 16/20 | 0.72 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22552034 | 0.93 | ADORA2A (0.71) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22552139 | 0.93 | ADORA2A (0.71) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21722869 | 0.93 | ADORA2A (0.71) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21730375 | 0.92 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21722490 | 0.92 | ADORA2A (0.77) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551839 | 0.91 | ADORA2A (0.67) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551854 | 0.88 | ADORA2A (0.85) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22552006 | 0.88 | ADORA2A (0.85) | ADORA2AADORA1ADORA2B | |
| SCHEMBL21722395 | 0.88 | ADORA2A (0.85) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22551786 | 0.86 | ADORA2A (0.76) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3837250-A1 | PYRAZINE COMPOUNDS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD (CN) | 2021-06-23 | — | — | EP | disclosed |
| WO-2020035052-A1 | PYRAZINE COMPOUNDS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2020-02-20 | — | — | WO | disclosed |