SCHEMBL2172329

SCHEMBL2172329

C=CCO[C@H]1O[C@H](CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.47
SSTR1 P30872 3/20 0.42
SSTR2 P30874 3/20 0.42
SSTR4 P31391 3/20 0.42
SSTR3 P32745 3/20 0.42
SSTR5 P35346 3/20 0.42
PTPN1 P18031 5/20 0.42
CDC25B P30305 5/20 0.42
TACR2 P21452 1/20 0.41
BCHE P06276 1/20 0.40
PTPN2 P17706 2/20 0.40
PTPN6 P29350 2/20 0.40
PTPN11 Q06124 2/20 0.40
PDPK1 O15530 1/20 0.40
MTOR P42345 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL181126 1.00 SLC6A2 (0.47) SLC6A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL181077 1.00 SLC6A2 (0.47) SLC6A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL181127 1.00 SLC6A2 (0.47) SLC6A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL16581477 1.00 SLC6A2 (0.47) SLC6A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL6929599 1.00 SLC6A2 (0.47) SLC6A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL9853879 0.96 SLC6A2 (0.47) SLC6A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL9853878 0.96 SLC6A2 (0.47) SLC6A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL1776774 0.95 SLC6A2 (0.47) SLC6A2SSTR1SSTR2SSTR4SSTR3
SCHEMBL13224920 0.90 SLC6A2 (0.56) SLC6A2BCHE
SCHEMBL2536430 0.90 SLC6A2 (0.56) SLC6A2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2627691-B1 DEGRADABLE POLYCARBONATES TEXAS A&M UNIV (US) 2020-11-25 EP disclosed
US-10052373-B2 Protein and peptide-free synthetic vaccines against Streptococcus pneumoniae type 3 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2018-08-21 US disclosed
EP-3046587-B1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS (DE) 2018-01-31 EP disclosed
US-20160279224-A1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-09-29 US disclosed
EP-2851092-A1 Protein and peptide-free synthetic vaccines against streptococcus pneumoniae type 3 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-03-25 EP disclosed
EP-2627691-A1 DEGRADABLE POLYCARBONATES Texas A&M University (US) 2013-08-21 EP disclosed
WO-2012051448-A1 DEGRADABLE POLYCARBONATES TEXAS A&M UNIVERSITY (US) 2012-04-19 WO disclosed
EP-2388264-A1 COMPOUND RETAINED IN TUMOR Toyo Suisan Kaisha, Ltd. (JP) 2011-11-23 EP disclosed
US-20110254443-A1 PHASE AND FREQUENCY LOCKED MAGNETRON MUONS, INC. 2011-10-20 US disclosed
US-7973145-B2 Sulfonated sugar compounds, pharmaceutical compositions which contain the same, and methods of treating tumors with the same TOYO SUISAN KAISHA, LTD. (JP) 2011-07-05 US disclosed
US-20100298246-A1 Sulfonated sugar compounds, pharmaceutical compositions which contain the same, and methods of treating tumors with the same TOYO SUISAN KAISHA, LTD. (JP) 2010-11-25 US disclosed
US-20100298246-A1 Sulfonated sugar compounds, pharmaceutical compositions which contain the same, and methods of treating tumors with the same TOYO SUISAN KAISHA, LTD. (JP) 2010-11-25 US disclosed
US-20100202971-A1 COMPOUND HAVING TUMOR-RESIDENT PROPERTY OHTA KEISUKE 2010-08-12 US disclosed
EP-2130834-A1 NOVEL SULFONATED SUGAR DERIVATIVE, AND USE THEREOF FOR MEDICINAL AGENT Toyo Suisan Kaisha, Ltd. (JP) 2009-12-09 EP disclosed
US-20090209475-A1 Sulfonated sugar compounds, pharmaceutical compositions which contain the same, and methods of treating tumors with the same TOYO SUISAN KAISHA, LTD. (JP) 2009-08-20 US disclosed
US-20090209475-A1 Sulfonated sugar compounds, pharmaceutical compositions which contain the same, and methods of treating tumors with the same TOYO SUISAN KAISHA, LTD. (JP) 2009-08-20 US disclosed
EP-0642799-B1 Improved prodrugs for enzyme mediated activation HOECHST AG (DE) 2001-11-07 EP disclosed
US-5621002-A HAVING A MODIFIED COMPETITIVE ENZYME ACTIVITY INHBITOR LINKED TO A SPACER-DRUG; ENZYME CLEAVAGE AT A LOWER CONCENTRATION, I.E. LOW MICHAELIS-MENTEN CONSTANT(KM) BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1997-04-15 US disclosed
EP-0642799-A1 Improved prodrugs for enzyme mediated activation BEHRINGWERKE Aktiengesellschaft (DE) 1995-03-15 EP disclosed
US-4818816-A ANTICOAGULANT CHOAY, S.A. (FR) 1989-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298246-A1 Sulfonated sugar compounds, pharmaceutical compositions which contain the same, and methods of treating tumors with the same SLC5A2, SLC5A1, DEGS1 SLC6A2 2314/4885SSTR1 820/4885SSTR2 521/4885
US-10052373-B2 Protein and peptide-free synthetic vaccines against Streptococcus pneumoniae type 3 STT3A, DDOST, LGALS3BP SLC6A2 4364/4885SSTR1 1795/4885SSTR2 1874/4885
US-20100202971-A1 COMPOUND HAVING TUMOR-RESIDENT PROPERTY HRH3, HRH4, HNRNPH3 SLC6A2 2975/4885SSTR1 417/4885SSTR2 529/4885
US-20090209475-A1 Sulfonated sugar compounds, pharmaceutical compositions which contain the same, and methods of treating tumors with the same SLC5A2, SLC5A1, DEGS1 SLC6A2 2314/4885SSTR1 820/4885SSTR2 521/4885
US-20160279224-A1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 STT3A, DDOST, LGALS3BP SLC6A2 4364/4885SSTR1 1795/4885SSTR2 1874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.