SCHEMBL21724147

SCHEMBL21724147

CCCCCCCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C)C(=O)OC

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BIRC2 Q13490 1/20 0.51
FAAH O00519 2/20 0.49
MEN1 O00255 1/20 0.49
MAPK1 P28482 1/20 0.49
KMT2A Q03164 1/20 0.49
NOD1 Q9Y239 6/20 0.45
DNM1 Q05193 1/20 0.44
PLA2G10 O15496 2/20 0.44
LPAR3 Q9UBY5 4/20 0.43
LPAR1 Q92633 2/20 0.42
PTPN1 P18031 1/20 0.42
PLA2G2C Q5R387 1/20 0.42
CPT2 P23786 1/20 0.41
CPT1A P50416 1/20 0.41
CPT1B Q92523 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21724149 1.00 BIRC2 (0.51) BIRC2FAAHMEN1MAPK1KMT2A
SCHEMBL21724226 1.00 BIRC2 (0.51) BIRC2FAAHMEN1MAPK1KMT2A
SCHEMBL21732832 1.00 BIRC2 (0.51) BIRC2FAAHMEN1MAPK1KMT2A
SCHEMBL21724505 1.00 BIRC2 (0.51) BIRC2FAAHMEN1MAPK1KMT2A
SCHEMBL21724524 1.00 BIRC2 (0.51) BIRC2FAAHMEN1MAPK1KMT2A
SCHEMBL21724526 1.00 BIRC2 (0.51) BIRC2FAAHMEN1MAPK1KMT2A
SCHEMBL21724145 1.00 BIRC2 (0.51) BIRC2FAAHMEN1MAPK1KMT2A
SCHEMBL21724273 0.90 BIRC2 (0.51) BIRC2FAAHMEN1MAPK1KMT2A
SCHEMBL21724274 0.90 BIRC2 (0.51) BIRC2FAAHMEN1MAPK1KMT2A
SCHEMBL21724663 0.89 BIRC2 (0.46) BIRC2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240398966-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2024-12-05 US disclosed
US-11998610-B2 Conjugates and methods of using the same FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2024-06-04 US disclosed
EP-3836971-A1 CONJUGATES AND METHODS OF USING THE SAME Flagship Pioneering Innovations V, Inc. (US) 2021-06-23 EP disclosed
US-20210162057-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-06-03 US disclosed
WO-2020037009-A1 CONJUGATES AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2020-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11998610-B2 Conjugates and methods of using the same CD47, CD44, CD74 BIRC2 1554/4885FAAH 2742/4885MEN1 2346/4885
US-20210162057-A1 CONJUGATES AND METHODS OF USING THE SAME CD47, CD44, CD74 BIRC2 1554/4885FAAH 2742/4885MEN1 2346/4885
US-20240398966-A1 CONJUGATES AND METHODS OF USING THE SAME CD47, CD44, CD74 BIRC2 1554/4885FAAH 2742/4885MEN1 2346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.