Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775348 | 0.84 | CYP3A4 (0.45) | MEN1KMT2AGAACYP2C9CYP2C19 | |
| SCHEMBL530398 | 0.84 | CYP2C9 (0.56) | MEN1KMT2AGAACYP2C9CYP2C19 | |
| SCHEMBL14790946 | 0.82 | MEN1 (0.51) | MEN1KMT2AGAACYP2C9CYP2C19 | |
| SCHEMBL19979597 | 0.81 | CYP3A4 (0.45) | MEN1KMT2AGAACYP2C9CYP2C19 | |
| SCHEMBL19979584 | 0.81 | CYP2C9 (0.56) | MEN1KMT2AGAACYP2C9CYP2C19 | |
| SCHEMBL14782075 | 0.79 | MEN1 (0.50) | MEN1KMT2AGAACYP2C9CYP2C19 | |
| SCHEMBL14782070 | 0.77 | MEN1 (0.41) | MEN1KMT2AGAACYP2C9CYP2C19 | |
| SCHEMBL14852896 | 0.76 | CYP2C9 (0.49) | MEN1KMT2AGAACYP2C9CYP2C19 | |
| SCHEMBL14790949 | 0.76 | MEN1 (0.45) | MEN1KMT2AGAACYP2C9CYP2C19 | |
| SCHEMBL7453693 | 0.76 | TSHR (0.56) | MEN1KMT2ACYP2C9TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10563146-B2 | Preparation and use of aminoalkylphosphonic acid dilakyl ester compounds in a lubricant for antiwear, friction reduction, and/or micropitting prevention | AFTON CHEMICAL CORPORATION (US) | 2020-02-18 | — | — | US | disclosed |