⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13361537 | 0.97 | — | — | |
| SCHEMBL15423459 | 0.88 | — | — | |
| SCHEMBL9450417 | 0.81 | — | — | |
| SCHEMBL1795836 | 0.78 | — | — | |
| SCHEMBL11989436 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL6032324 | 0.75 | — | — | |
| SCHEMBL2704280 | 0.74 | — | — | |
| SCHEMBL16191156 | 0.73 | — | — | |
| SCHEMBL23251449 | 0.71 | — | — | |
| SCHEMBL20808119 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002254-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2021-01-07 | — | — | US | disclosed |
| US-10562884-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-02-18 | — | — | US | disclosed |