Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858456 | 0.85 | ERCC1 (0.58) | HSD11B1KCNH2CACNA1IHDAC1SMN1; SMN2 | |
| SCHEMBL17285705 | 0.85 | HDAC4 (0.65) | HSD11B1KCNH2HDAC1SMN1; SMN2HTT | |
| SCHEMBL14067363 | 0.84 | SMN1; SMN2 (0.68) | HDAC1SMN1; SMN2HTTLMNANPSR1 | |
| SCHEMBL3521822 | 0.83 | HDAC1 (0.55) | HSD11B1KCNH2CACNA1IHDAC1SMN1; SMN2 | |
| SCHEMBL2863340 | 0.82 | KMT2A (0.55) | HSD11B1KCNH2CACNA1IHDAC1SMN1; SMN2 | |
| SCHEMBL13448598 | 0.81 | HDAC1 (0.56) | HSD11B1KCNH2CACNA1IHDAC1SMN1; SMN2 | |
| SCHEMBL2844463 | 0.81 | HDAC4 (0.70) | HSD11B1HDAC1HDAC4P2RX7 | |
| SCHEMBL24181164 | 0.81 | SMN1; SMN2 (0.55) | HSD11B1KCNH2CACNA1IHDAC1SMN1; SMN2 | |
| SCHEMBL20060916 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL2854860 | 0.79 | SMN1; SMN2 (0.62) | HSD11B1SMN1; SMN2HTTTRPA1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562878-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SUNOVION PHARAMCEUTICALS INC. (US) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562878-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SLC18A2, SLC6A2, SLC18A3 | HSD11B1 919/4885KCNH2 430/4885CACNA1I 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.