Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 3/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20697361 | 0.86 | KDM4E (0.42) | MDM2TYK2 | |
| SCHEMBL20689335 | 0.78 | KDM4E (0.43) | — | |
| SCHEMBL20687945 | 0.76 | KDM4E (0.44) | TYK2 | |
| SCHEMBL20697307 | 0.75 | TYK2 (0.48) | TYK2 | |
| SCHEMBL20689457 | 0.74 | TYK2 (0.52) | TYK2 | |
| SCHEMBL21285355 | 0.73 | TYK2 (0.51) | TYK2 | |
| SCHEMBL20697392 | 0.73 | TYK2 (0.52) | TYK2 | |
| SCHEMBL21961793 | 0.73 | KDM4E (0.42) | MDM2TYK2 | |
| SCHEMBL21947270 | 0.72 | TYK2 (0.38) | TYK2 | |
| SCHEMBL21238680 | 0.68 | CDK7 (0.33) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562906-B2 | TYK2 inhibitors and uses thereof | Nimbus Lakshimi, Inc. (US) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562906-B2 | TYK2 inhibitors and uses thereof | TYK2, JAK2, JAK1 | MDM2 1285/4885TYK2 1/4885GPR119 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.