Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | SLC10A1 | Q14973 | 5/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 7/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16257319 | 0.89 | GRM4 (0.41) | GRM4SLC10A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL16257389 | 0.89 | GRM4 (0.41) | GRM4SLC10A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL21727644 | 0.88 | GRM4 (0.40) | GRM4SLC10A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL16257386 | 0.88 | GRM4 (0.40) | GRM4SLC10A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL16257246 | 0.88 | GRM4 (0.40) | GRM4SLC10A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL16257248 | 0.88 | GRM4 (0.40) | GRM4SLC10A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL16257211 | 0.87 | GRM4 (0.40) | GRM4SLC10A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL17700917 | 0.87 | GRM4 (0.40) | GRM4SLC10A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL17700879 | 0.87 | GRM4 (0.42) | GRM4SLC10A1ABCC9ABCC8KCNJ11 | |
| SCHEMBL16257191 | 0.87 | GRM4 (0.42) | GRM4SLC10A1ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121164-B1 | SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2020-02-19 | — | — | EP | disclosed |