Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | F11 | P03951 | 4/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.36 |
| ▸ | SLC10A1 | Q14973 | 5/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21727542 | 0.90 | GRM4 (0.45) | GRM4XDHARF11KLKB1 | |
| SCHEMBL17700846 | 0.86 | GRM4 (0.42) | GRM4XDHARF11KLKB1 | |
| SCHEMBL16257441 | 0.80 | GRM4 (0.42) | GRM4MAPTARF11KLKB1 | |
| SCHEMBL20164936 | 0.80 | GRM4 (0.42) | GRM4MAPTARF11KLKB1 | |
| SCHEMBL16257404 | 0.80 | GRM4 (0.44) | GRM4LMNATP53MAPTAR | |
| SCHEMBL19842053 | 0.79 | GRM4 (0.42) | GRM4ARF11KLKB1SLC10A1 | |
| SCHEMBL18407922 | 0.77 | GRM4 (0.41) | GRM4ARPGR | |
| SCHEMBL16257209 | 0.77 | GRM4 (0.41) | GRM4ARPGR | |
| SCHEMBL16257206 | 0.77 | GRM4 (0.41) | GRM4ARPGR | |
| SCHEMBL22579501 | 0.77 | GRM4 (0.42) | GRM4ARSLC10A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121164-B1 | SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2020-02-19 | — | — | EP | disclosed |