Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 18/20 | 0.72 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.45 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12069488 | 0.84 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL21727913 | 0.81 | SLC22A12 (0.71) | SLC22A12SLC22A6SLC22A11ABCG2CYP11B1 | |
| SCHEMBL21758473 | 0.75 | SLC22A12 (0.56) | SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL21397227 | 0.74 | SLC22A12 (0.54) | SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL21727932 | 0.73 | SLC22A12 (0.62) | SLC22A12 | |
| SCHEMBL12069490 | 0.71 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A11 | |
| SCHEMBL21727928 | 0.70 | SLC22A12 (0.69) | SLC22A12 | |
| SCHEMBL21727923 | 0.70 | SLC22A12 (0.65) | SLC22A12 | |
| SCHEMBL6921971 | 0.69 | SLC22A12 (0.54) | SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL21727870 | 0.69 | SLC22A12 (0.66) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611167-A1 | THIOACETATE COMPOUND AND METHODS OF USE | Ardea Biosciences, Inc. (US) | 2020-02-19 | — | — | EP | disclosed |