Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20126461 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT3SIRT5HTT | |
| SCHEMBL18822243 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT3SIRT5HTT | |
| SCHEMBL24220963 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT3SIRT5HTT | |
| SCHEMBL19622145 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1SIRT3SIRT5HTT | |
| SCHEMBL25655950 | 0.91 | FURIN (0.41) | SIRT2SIRT1SIRT3SIRT5HTT | |
| SCHEMBL16769624 | 0.91 | FURIN (0.41) | SIRT2SIRT1SIRT3SIRT5HTT | |
| SCHEMBL22268356 | 0.90 | SIRT2 (0.44) | SIRT2SIRT1SIRT3SIRT5HTT | |
| SCHEMBL24220965 | 0.90 | SIRT2 (0.44) | SIRT2SIRT1SIRT3SIRT5HTT | |
| SCHEMBL25124339 | 0.90 | FURIN (0.43) | SIRT2SIRT1SIRT3SIRT5HTT | |
| SCHEMBL24115319 | 0.89 | SIRT2 (0.40) | SIRT2SIRT1SIRT3SIRT5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3610889-A1 | PROTEIN-ACTIVE AGENT CONJUGATES AND METHOD FOR PREPARING THE SAME | LegoChem Biosciences, Inc. (KR) | 2020-02-19 | — | — | EP | disclosed |