Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398605 | 1.00 | GAA (0.57) | GAAIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL28737232 | 0.91 | GAA (0.50) | GAAIDO1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL7271091 | 0.88 | GAA (0.48) | GAAIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL29770447 | 0.88 | GAA (0.46) | GAAIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL440693 | 0.88 | GAA (0.46) | GAAIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL11602223 | 0.84 | NOTUM (0.44) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13247609 | 0.83 | GAA (0.46) | GAAIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL21384555 | 0.82 | GAA (0.46) | GAAIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL30296285 | 0.82 | GAA (0.40) | GAAIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL9728339 | 0.82 | GAA (0.40) | GAAIDO1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912501-B | Method for preparing 4-trifluoromethyl aniline by continuous catalytic hydrogenation dechlorination | 浙江巍华新材料股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-116143633-A | Method for preparing 2, 5-dichloro-4-trifluoromethyl aniline | 浙江巍华新材料股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-113912501-A | Method for preparing 4-trifluoromethylaniline through continuous catalytic hydrodechlorination | 浙江巍华新材料股份有限公司 | 2022-01-11 | — | — | CN | claimed |
| WO-2024153155-A1 | DOUBLE-HETEROCYCLIC WRN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 成都微芯药业有限公司 | 2024-07-25 | — | — | WO | disclosed |
| WO-2024149389-A1 | SUBSTITUTED BRIDGE RING INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2024-07-18 | — | — | WO | disclosed |
| CN-113912501-B | Method for preparing 4-trifluoromethyl aniline by continuous catalytic hydrogenation dechlorination | 浙江巍华新材料股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023179629-A1 | SUBSTITUTED BRIDGED RING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-09-28 | — | — | WO | disclosed |
| CN-116143633-A | Method for preparing 2, 5-dichloro-4-trifluoromethyl aniline | 浙江巍华新材料股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-113912501-A | Method for preparing 4-trifluoromethylaniline through continuous catalytic hydrodechlorination | 浙江巍华新材料股份有限公司 | 2022-01-11 | — | — | CN | disclosed |
| EP-2773616-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-19 | — | — | EP | disclosed |