Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | TEC | P42680 | 8/20 | 0.42 |
| ▸ | TXK | P42681 | 8/20 | 0.42 |
| ▸ | BMX | P51813 | 8/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21729279 | 0.93 | BTK (0.49) | BTKTECTXKBMX | |
| SCHEMBL19001745 | 0.89 | BTK (0.63) | BTKTECTXKBMX | |
| SCHEMBL19001730 | 0.87 | BTK (0.51) | BTKNR3C1TECTXKBMX | |
| SCHEMBL20847966 | 0.86 | BTK (0.60) | BTKTECTXKBMX | |
| SCHEMBL19836219 | 0.85 | BTK (0.48) | BTKNR3C1TECTXKBMX | |
| SCHEMBL19836029 | 0.84 | BTK (0.61) | BTKTECTXKBMX | |
| SCHEMBL21729249 | 0.83 | BTK (0.49) | BTKNR3C1TECTXKBMX | |
| SCHEMBL19002022 | 0.81 | BTK (0.55) | BTKTECTXKBMX | |
| SCHEMBL19002017 | 0.81 | BTK (0.63) | BTKTECTXKBMX | |
| SCHEMBL19002028 | 0.81 | BTK (0.45) | BTKTECTXKBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055843-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055843-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BTK, SYK, LCK | BTK 1/4885NR3C1 593/4885TEC 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.