Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979964 | 0.87 | LOX (0.49) | HCRTR1HCRTR2IRAK4LOXLOXL2 | |
| SCHEMBL16695529 | 0.87 | LOX (0.49) | HCRTR1HCRTR2IRAK4LOXLOXL2 | |
| SCHEMBL17448838 | 0.83 | HCRTR1 (0.47) | HCRTR1HCRTR2LOXLOXL2AVPR1A | |
| SCHEMBL20266990 | 0.81 | LOX (0.54) | HCRTR1HCRTR2LOXLOXL2AVPR1A | |
| SCHEMBL25323010 | 0.81 | HCRTR1 (0.43) | HCRTR1HCRTR2LOXLOXL2AVPR1A | |
| SCHEMBL18159813 | 0.80 | HCRTR1 (0.44) | HCRTR1HCRTR2IRAK4LOXLOXL2 | |
| SCHEMBL18150702 | 0.80 | HCRTR1 (0.44) | HCRTR1HCRTR2IRAK4LOXLOXL2 | |
| SCHEMBL18150701 | 0.80 | HCRTR1 (0.44) | HCRTR1HCRTR2IRAK4LOXLOXL2 | |
| SCHEMBL30001347 | 0.80 | LOX (0.60) | HCRTR1HCRTR2LOXLOXL2AVPR1A | |
| SCHEMBL21723114 | 0.78 | HCRTR1 (0.45) | HCRTR1HCRTR2LOXLOXL2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035466-A1 | NOVEL SULFONEUREA COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-02-20 | — | — | WO | disclosed |