Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19497390 | 0.80 | GAA (0.45) | GAAPOLBRAB9ANPC1LMNA | |
| SCHEMBL22436865 | 0.80 | GAA (0.32) | GAAPOLBRAB9ANPC1LMNA | |
| SCHEMBL13799634 | 0.72 | HTT (0.40) | GAAKDM4EPOLBRAB9ANPC1 | |
| SCHEMBL22198889 | 0.71 | SMN1; SMN2 (0.44) | KDM4E | |
| SCHEMBL14039865 | 0.70 | — | — | |
| SCHEMBL30615 | 0.69 | — | — | |
| SCHEMBL12926030 | 0.69 | — | — | |
| SCHEMBL28618701 | 0.69 | — | — | |
| SCHEMBL21835472 | 0.67 | SMN1; SMN2 (0.38) | GAAKDM4EPOLBRAB9ANPC1 | |
| SCHEMBL21835474 | 0.65 | SMN1; SMN2 (0.38) | GAAKDM4EPOLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445767-B1 | MACROCYCLIC MCL1 INHIBITORS FOR TREATING CANCER | ASTRAZENECA AB (SE) | 2020-02-19 | — | — | EP | disclosed |