Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.57 |
| ▸ | LIPE | Q05469 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1677139 | 0.91 | EPHX2 (0.57) | EPHX2LIPEEPHX1DPP4MMP2 | |
| SCHEMBL1676913 | 0.89 | EPHX2 (0.63) | EPHX2LIPEEPHX1DPP4MMP2 | |
| SCHEMBL1676930 | 0.86 | EPHX2 (0.52) | EPHX2LIPEEPHX1DPP4MMP2 | |
| SCHEMBL1677155 | 0.86 | EPHX2 (0.54) | EPHX2LIPEEPHX1DPP4MEN1 | |
| SCHEMBL1677130 | 0.86 | EPHX2 (0.52) | EPHX2LIPEEPHX1DPP4MMP2 | |
| SCHEMBL1677178 | 0.85 | EPHX2 (0.64) | EPHX2LIPEEPHX1DPP4MMP2 | |
| SCHEMBL1677118 | 0.85 | EPHX2 (0.60) | EPHX2LIPEEPHX1DPP4MMP2 | |
| SCHEMBL1677075 | 0.84 | EPHX2 (0.56) | EPHX2LIPEEPHX1DPP4MMP2 | |
| SCHEMBL1677127 | 0.83 | EPHX2 (0.53) | EPHX2LIPEEPHX1DPP4MMP2 | |
| SCHEMBL1676948 | 0.83 | EPHX2 (0.70) | EPHX2LIPEEPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346820-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | Shionogi & Co., Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |