Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 15/20 | 0.63 |
| ▸ | PAK1 | Q13153 | 4/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21243874 | 0.88 | KRAS (0.79) | KRAS | |
| SCHEMBL21243889 | 0.88 | KRAS (0.79) | KRAS | |
| SCHEMBL21243920 | 0.88 | KRAS (0.79) | KRAS | |
| SCHEMBL24854607 | 0.87 | KRAS (0.78) | KRASPAK1RPS6KB1 | |
| SCHEMBL21733404 | 0.87 | KRAS (0.78) | KRASPAK1RPS6KB1 | |
| SCHEMBL30178135 | 0.87 | KRAS (0.78) | KRASPAK1RPS6KB1 | |
| SCHEMBL21733401 | 0.87 | KRAS (0.78) | KRASPAK1RPS6KB1 | |
| SCHEMBL21733402 | 0.87 | KRAS (0.78) | KRASPAK1RPS6KB1 | |
| SCHEMBL21734025 | 0.87 | KRAS (0.78) | KRASPAK1RPS6KB1 | |
| SCHEMBL30177726 | 0.87 | KRAS (0.78) | KRASPAK1RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035031-A1 | FUSED RING COMPOUNDS | GENENTECH, INC. (US) | 2020-02-20 | — | — | WO | disclosed |