Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.50 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.50 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12406606 | 1.00 | AURKA (0.53) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| Cyclohexane SCHEMBL15204208 | 0.87 | AURKA (0.59) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2174408 | 0.87 | AURKA (0.56) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2174406 | 0.87 | AURKA (0.56) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2171887 | 0.85 | AURKA (0.55) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2171893 | 0.85 | AURKA (0.55) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2173236 | 0.84 | AURKA (0.53) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2173232 | 0.84 | AURKA (0.53) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2172295 | 0.83 | KDR (0.58) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2172299 | 0.83 | KDR (0.58) | AURKAMTORPRKAG1PRKAA1PRKAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973062-B2 | Androgen receptor-ablative agents | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-07-05 | — | — | US | claimed |
| US-7973062-B2 | Androgen receptor-ablative agents | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-07-05 | — | — | US | disclosed |