Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065159 | 0.94 | IDH1 (0.61) | IDH1 | |
| SCHEMBL17601180 | 0.94 | IDH1 (0.61) | IDH1 | |
| SCHEMBL17601178 | 0.94 | IDH1 (0.61) | IDH1 | |
| Hydrochloric Acid SCHEMBL17601421 | 0.93 | IDH1 (0.61) | IDH1 | |
| SCHEMBL21735715 | 0.88 | IDH1 (0.52) | IDH1 | |
| SCHEMBL30065246 | 0.87 | IDH1 (0.58) | IDH1 | |
| SCHEMBL17601152 | 0.87 | IDH1 (0.58) | IDH1 | |
| SCHEMBL17601153 | 0.87 | IDH1 (0.58) | IDH1 | |
| Hydrochloric Acid SCHEMBL17601587 | 0.86 | IDH1 (0.57) | IDH1 | |
| Hydrochloric Acid SCHEMBL17601586 | 0.86 | IDH1 (0.57) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3447050-B1 | PYRIDIN-2(1H)-ONE QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-19 | — | — | EP | disclosed |