SCHEMBL2173708

SCHEMBL2173708

O=C(O)c1ccc2c3ccc(C(=O)O)c4c(C(=O)O)ccc(c5cccc1c52)c43

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.58
TYMS P04818 1/20 0.53
NR4A1 P22736 1/20 0.50
NR4A2 P43354 1/20 0.50
NR4A3 Q92570 1/20 0.50
KDM4E B2RXH2 6/20 0.46
L3MBTL1 Q9Y468 5/20 0.46
ALDH1A1 P00352 4/20 0.46
POLB P06746 4/20 0.46
RECQL P46063 2/20 0.46
CASP6 P55212 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
APOBEC3A P31941 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
PARP1 P09874 1/20 0.46
KMT2A Q03164 3/20 0.46
CAMKK1 Q8N5S9 2/20 0.46
CAMKK2 Q96RR4 2/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28989 0.94 TYMS (0.58) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL28007 0.94 TYMS (0.58) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL29450078 0.94 TYMS (0.58) CYP1A2TYMSNR4A1NR4A2NR4A3
Formic Acid SCHEMBL28707649 0.93 CYP1A2 (0.50) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL11335171 0.91 TYMS (0.56) CYP1A2TYMSNR4A1NR4A2NR4A3
Hydrochloric Acid SCHEMBL8901377 0.91 TYMS (0.56) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL14052567 0.91 TYMS (0.56) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL2804453 0.89 CYP1A2 (0.47) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL8541145 0.87 CYP1A2 (0.48) CYP1A2TYMSNR4A1NR4A2NR4A3
SCHEMBL5858488 0.87 CYP1A2 (0.48) CYP1A2TYMSNR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3143067-B1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-09-13 EP claimed
EP-3143067-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS Huntsman Advanced Materials Americas LLC (US) 2017-03-22 EP claimed
US-20170051100-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2017-02-23 US claimed
WO-2015175583-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-11-19 WO claimed
EP-3143067-B1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-09-13 EP disclosed
CN-113999370-A Multifunctional polyamides for protective coatings 亨斯迈先进材料美国有限责任公司 2022-02-01 CN disclosed
US-10414855-B2 Multifunctional polyamides for protective coatings HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2019-09-17 US disclosed
EP-3143067-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS Huntsman Advanced Materials Americas LLC (US) 2017-03-22 EP disclosed
US-20170051100-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2017-02-23 US disclosed
US-20160060434-A1 STABILIZATION OF POLYAMIDE WITH COPPER-BASED METAL ORGANIC FRAMEWORKS BASF SE (DE) 2016-03-03 US disclosed
EP-2984131-A1 STABILIZATION OF POLYAMIDE WITH COPPER-BASED METAL ORGANIC FRAMEWORKS BASF SE (DE) 2016-02-17 EP disclosed
WO-2015175583-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-11-19 WO disclosed
WO-2014166865-A1 STABILIZATION OF POLYAMIDE WITH COPPER-BASED METAL ORGANIC FRAMEWORKS BASF SE (DE) 2014-10-16 WO disclosed
US-7973122-B2 Polyamideimide compositions having multifunctional core structures GENERAL CABLE TECHNOLOGIES CORPORATION (US) 2011-07-05 US disclosed
US-20080160304-A1 Polyamideimide compositions having multifunctional core structures GENERAL CABLE TECHNOLOGIES 2008-07-03 US disclosed
US-20050282010-A1 Polyamideimide compositions having multifunctional core structures GENERAL CABLE TECHNOLOGIES CORPORATION 2005-12-22 US disclosed
EP-0194058-B1 PROCESS OF PREPARING POLYAMIDES AND/OR POLYIMIDES MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-11-08 EP disclosed
US-4795795-A Catalytic preparation of polyamide or polyamide-polymide with N,N'-dimethyl alkylene urea solvent MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-01-03 US disclosed
EP-0194058-A2 Process of preparing polyamides and/or polyimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-09-10 EP disclosed
US-4395531-A Process for the preparation of polyamide compounds by the reaction of polycarboxylic acids with diisocyanates in the presence of at least one mono-alkali metal salt of dicarboxylic acid MITSUI TOATSU CHEMICAL INCORPORATED (JP) 1983-07-26 US disclosed