Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17454480 | 0.80 | LRRK2 (0.39) | LRRK2ACHECYP1A2IRAK4ADORA2A | |
| SCHEMBL15723801 | 0.78 | LRRK2 (0.39) | LRRK2ACHECYP1A2IRAK4ADORA2A | |
| SCHEMBL17452764 | 0.78 | LRRK2 (0.39) | LRRK2ACHECYP1A2IRAK4ADORA2A | |
| SCHEMBL18049567 | 0.78 | LRRK2 (0.39) | LRRK2ACHECYP1A2IRAK4ADORA2A | |
| SCHEMBL24238830 | 0.77 | LRRK2 (0.38) | LRRK2ACHECYP1A2IRAK4 | |
| SCHEMBL15723766 | 0.77 | LRRK2 (0.38) | LRRK2ACHECYP1A2IRAK4 | |
| SCHEMBL15723735 | 0.76 | NTRK1 (0.37) | LRRK2ACHECYP1A2IRAK4ADORA2A | |
| SCHEMBL13194751 | 0.76 | LRRK2 (0.37) | LRRK2ACHECYP1A2ADORA2AADORA1 | |
| SCHEMBL25288681 | 0.76 | LRRK2 (0.37) | LRRK2ACHECYP1A2IRAK4ADORA2A | |
| SCHEMBL23501964 | 0.74 | LRRK2 (0.36) | LRRK2ACHECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611165-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |