Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 17/20 | 0.61 |
| ▸ | TTK | P33981 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21738246 | 0.96 | LRRK2 (0.58) | LRRK2TTKDYRK1APTK2 | |
| SCHEMBL21738326 | 0.89 | LRRK2 (0.60) | LRRK2 | |
| SCHEMBL22264386 | 0.89 | LRRK2 (0.74) | LRRK2TTK | |
| SCHEMBL22264420 | 0.88 | TTK (0.72) | LRRK2TTK | |
| SCHEMBL22264408 | 0.87 | LRRK2 (0.74) | LRRK2TTK | |
| SCHEMBL21738324 | 0.87 | LRRK2 (0.63) | LRRK2DYRK1A | |
| SCHEMBL21738306 | 0.86 | LRRK2 (0.57) | LRRK2TTKDYRK1A | |
| SCHEMBL21738321 | 0.86 | LRRK2 (0.57) | LRRK2 | |
| SCHEMBL22264432 | 0.86 | LRRK2 (0.58) | LRRK2TTK | |
| SCHEMBL21738418 | 0.86 | TTK (0.76) | LRRK2TTKDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020036437-A1 | SUBSTITUTED HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING PROTEIN KINASE-RELATED DISEASES WHICH CONTAINS SAME AS ACTIVE INGREDIENT | 재단법인 대구경북첨단의료산업진흥재단 | 2020-02-20 | — | — | WO | disclosed |