Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 17/20 | 0.68 |
| ▸ | VEGFA | P15692 | 5/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18688473 | 0.83 | EPAS1 (0.71) | EPAS1VEGFA | |
| SCHEMBL18688474 | 0.83 | EPAS1 (0.71) | EPAS1VEGFA | |
| SCHEMBL16556281 | 0.81 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL21005070 | 0.81 | EPAS1 (0.67) | EPAS1VEGFA | |
| SCHEMBL16560969 | 0.79 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL17671198 | 0.79 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16555569 | 0.78 | EPAS1 (0.80) | EPAS1VEGFA | |
| SCHEMBL30856902 | 0.78 | EPAS1 (0.80) | EPAS1VEGFA | |
| SCHEMBL16555574 | 0.77 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL20224235 | 0.77 | EPAS1 (1.00) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3417851-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3417852-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2020-02-19 | — | — | EP | disclosed |