SCHEMBL21741933

SCHEMBL21741933

CCCCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)C

nearest known ligand 0.83

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.83
TLR8 Q9NR97 5/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25180432 0.97 TLR7 (0.78) TLR7TLR8
SCHEMBL30361618 0.92 TLR7 (0.82) TLR7TLR8
SCHEMBL24183877 0.92 TLR7 (0.82) TLR7TLR8
SCHEMBL7013310 0.91 TLR7 (1.00) TLR7TLR8
SCHEMBL25332759 0.91 TLR7 (0.80) TLR7TLR8
SCHEMBL29481132 0.91 TLR7 (1.00) TLR7TLR8
SCHEMBL25950229 0.91 TLR7 (0.80) TLR7TLR8
SCHEMBL24183875 0.90 TLR7 (0.78) TLR7TLR8
SCHEMBL30361688 0.90 TLR7 (0.78) TLR7TLR8
SCHEMBL24183876 0.90 TLR7 (0.78) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3166640-B1 COMBINATION THERAPY COMPOSITIONS AND METHODS FOR TREATING CANCERS BIRDIE BIOPHARMACEUTICALS INC (KY) 2023-06-14 EP disclosed
WO-2020037114-A1 COMPOSITIONS AND METHODS FOR THE MODULATION OF CYTOKINES GALLEON LABS LLC (US) 2020-02-20 WO disclosed