SCHEMBL21742016

SCHEMBL21742016

CCOC(CC)(c1ccccn1)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CHRM2 P08172 2/20 0.40
BLM P54132 1/20 0.35
CYP2D6 P10635 1/20 0.35
AHR P35869 1/20 0.34
HDAC6 Q9UBN7 2/20 0.34
GRM5 P41594 1/20 0.33
KCNA5 P22460 1/20 0.33
KCNH2 Q12809 1/20 0.33
LMNA P02545 1/20 0.33
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21742023 0.88 CHRM2 (0.42) SMN1; SMN2L3MBTL1CHRM2BLMCYP2D6
SCHEMBL21742072 0.86 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1CHRM2BLMCYP2D6
SCHEMBL21742381 0.85 SMN1; SMN2 (0.40) SMN1; SMN2L3MBTL1CHRM2AHRHDAC6
SCHEMBL21742056 0.84 AHR (0.40) SMN1; SMN2L3MBTL1CHRM2BLMCYP2D6
SCHEMBL21742052 0.80 SMN1; SMN2 (0.40) SMN1; SMN2L3MBTL1CHRM2BLMCYP2D6
SCHEMBL21742276 0.79 SMN1; SMN2 (0.44) SMN1; SMN2L3MBTL1CHRM2BLMCYP2D6
SCHEMBL21742075 0.79 SMN1; SMN2 (0.44) SMN1; SMN2L3MBTL1CHRM2BLMCYP2D6
SCHEMBL19222207 0.78 SMN1; SMN2 (0.47) SMN1; SMN2L3MBTL1CHRM2BLMCYP2D6
SCHEMBL21742092 0.77 SMN1; SMN2 (0.45) SMN1; SMN2L3MBTL1CHRM2BLMCYP2D6
SCHEMBL17976212 0.76 SMN1; SMN2 (0.48) SMN1; SMN2L3MBTL1CHRM2BLMCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611164-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed