Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742278 | 0.88 | SMN1; SMN2 (0.41) | CHRM2SMN1; SMN2L3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL21742267 | 0.81 | SMN1; SMN2 (0.44) | CHRM2SMN1; SMN2L3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL21742282 | 0.79 | CHRM2 (0.46) | CHRM2SMN1; SMN2L3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL21742270 | 0.79 | CYP2D6 (0.40) | CHRM2SMN1; SMN2L3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL21742067 | 0.76 | SMN1; SMN2 (0.37) | CHRM2SMN1; SMN2L3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL21742083 | 0.76 | CHRM2 (0.44) | CHRM2SMN1; SMN2L3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL21742196 | 0.76 | CHRM2 (0.44) | CHRM2SMN1; SMN2L3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL21742271 | 0.76 | CHRM2 (0.44) | CHRM2SMN1; SMN2L3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL21742049 | 0.75 | SMN1; SMN2 (0.43) | CHRM2SMN1; SMN2L3MBTL1CYP2D6CYP1A2 | |
| SCHEMBL22863374 | 0.72 | SMN1; SMN2 (0.50) | CHRM2SMN1; SMN2L3MBTL1CYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611164-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |