Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.86 |
| ▸ | AKT2 | P31751 | 14/20 | 0.86 |
| ▸ | AKT3 | Q9Y243 | 7/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802392 | 0.94 | AKT1 (0.87) | AKT1AKT2AKT3 | |
| SCHEMBL2176661 | 0.93 | AKT1 (1.00) | AKT1AKT2AKT3 | |
| SCHEMBL31455654 | 0.90 | AKT1 (0.88) | AKT1AKT2AKT3 | |
| SCHEMBL2190453 | 0.89 | AKT1 (0.74) | AKT1AKT2AKT3 | |
| SCHEMBL31420297 | 0.89 | AKT1 (0.74) | AKT1AKT2AKT3 | |
| SCHEMBL31455829 | 0.89 | AKT1 (0.86) | AKT1AKT2AKT3 | |
| SCHEMBL2190884 | 0.88 | AKT1 (1.00) | AKT1AKT2AKT3 | |
| SCHEMBL31455740 | 0.88 | AKT1 (0.85) | AKT1AKT2AKT3 | |
| SCHEMBL2177082 | 0.88 | AKT1 (0.77) | AKT1AKT2AKT3 | |
| SCHEMBL2175106 | 0.87 | AKT1 (1.00) | AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519522-A2 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ArQule, Inc. (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082270-A2 | SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS | ARQULE. INC. (US) | 2011-07-07 | — | — | WO | disclosed |