SCHEMBL21742284

SCHEMBL21742284

CCCOC(CC)(c1ccccn1)C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 2/20 0.38
CHRM2 P08172 6/20 0.36
CHRM3 P20309 6/20 0.36
CHRM4 P08173 3/20 0.34
CHRM1 P11229 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 2/20 0.33
NPC1 O15118 2/20 0.33
GRM5 P41594 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP19A1 P11511 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21742025 0.99 MEN1 (0.39) MEN1KMT2ACHRM2CHRM3CHRM4
SCHEMBL21742272 0.96 CHRM2 (0.37) MEN1KMT2ACHRM2CHRM3CHRM1
SCHEMBL21742260 0.86 CHRM3 (0.38) MEN1KMT2ACHRM2CHRM3SMN1; SMN2
SCHEMBL21742189 0.85 AHR (0.35) MEN1KMT2ACHRM2CHRM3SMN1; SMN2
SCHEMBL21742058 0.84 AHR (0.36) MEN1KMT2ACHRM2CHRM3SMN1; SMN2
SCHEMBL21742277 0.83 CHRM3 (0.40) MEN1KMT2ACHRM2CHRM3SMN1; SMN2
SCHEMBL21742019 0.82 SMN1; SMN2 (0.38) MEN1KMT2ACHRM2CHRM3SMN1; SMN2
SCHEMBL21742275 0.80 SMN1; SMN2 (0.38) MEN1KMT2ACHRM2CHRM3SMN1; SMN2
SCHEMBL21742173 0.78 MEN1 (0.37) MEN1KMT2ACHRM2CHRM3SMN1; SMN2
SCHEMBL21742361 0.78 AHR (0.37) CHRM2CHRM3SMN1; SMN2L3MBTL1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611164-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed