SCHEMBL21742285

SCHEMBL21742285

CCC(F)(CC(C)C)c1ccccn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
AHR P35869 1/20 0.36
CHRM3 P20309 1/20 0.35
CYP1A2 P05177 4/20 0.34
ALDH1A1 P00352 2/20 0.34
CYP2C19 P33261 1/20 0.34
KCNH2 Q12809 2/20 0.34
TSHR P16473 2/20 0.34
SLC22A2 O15244 1/20 0.34
SLC22A1 O15245 1/20 0.34
PGR P06401 1/20 0.34
THRB P10828 1/20 0.34
ADRB3 P13945 1/20 0.34
OPRK1 P41145 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
PDE3A Q14432 1/20 0.34
SLC47A1 Q96FL8 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21742028 0.86 SMN1; SMN2 (0.48) SMN1; SMN2L3MBTL1AHRCYP1A2KCNH2
SCHEMBL21742422 0.78 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1AHRCHRM3CYP1A2
SCHEMBL12705289 0.78 SMN1; SMN2 (0.41) SMN1; SMN2L3MBTL1CHRM3CYP1A2ALDH1A1
SCHEMBL21742006 0.77 SMN1; SMN2 (0.48) SMN1; SMN2L3MBTL1AHRCHRM3CYP1A2
SCHEMBL21742119 0.77 SMN1; SMN2 (0.40) SMN1; SMN2L3MBTL1CHRM3CYP1A2ALDH1A1
SCHEMBL21742384 0.76 SMN1; SMN2 (0.37) SMN1; SMN2L3MBTL1AHRCYP1A2ALDH1A1
SCHEMBL21742380 0.75 SMN1; SMN2 (0.39) SMN1; SMN2L3MBTL1AHRCHRM3CYP1A2
SCHEMBL21742374 0.75 SMN1; SMN2 (0.47) SMN1; SMN2L3MBTL1AHRCHRM3CYP1A2
SCHEMBL12705444 0.75 SMN1; SMN2 (0.45) SMN1; SMN2L3MBTL1CHRM3CYP1A2ALDH1A1
SCHEMBL21742204 0.75 AHR (0.36) SMN1; SMN2L3MBTL1AHRCYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611164-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed